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CS-W001157 4
Total: USD 88.00

Cyclooct-4-enol

  • CAS No. 4277-34-3

  • Cat. No. CS-W006126
  • Purity≥96%
  • MDL No.MFCD06252442

*For research and further manufacturing use only, not for direct human use.

Cyclooct-4-enol|CS-W006126

Structure of 4277-34-3

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General Information

  • CAS No. 4277-34-3
  • Cat. No. CS-W006126
  • Purity ≥96%
  • MDL No. MFCD06252442
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O
  • Molecular Weight 126.20
  • Synonym(s) None
  • SMILES OC1CC/C=C\CCC1

Description

Cyclooct-4-enol is a strained, electron-rich cyclic enol featuring a conjugated diene system within an eight-membered ring. This labile structure exhibits enhanced reactivity in electrophilic addition and cycloaddition processes due to ring strain and oxygen lone-pair delocalization. The hydroxyl group enables direct functionalization or derivatization under mild conditions, facilitating access to complex carbocyclic architectures.

Application

Cyclooct-4-enol serves as a versatile synthetic intermediate for strained ring systems and functionalized cycloalkenes. Its conjugated enol functionality enables direct participation in electrophilic additions, Diels–Alder reactions, and metal-catalyzed transformations. The molecule exhibits sufficient bench stability for routine handling and facilitates clean functionalization at the hydroxyl and alkene sites, making it valuable for constructing complex heterocyclic scaffolds and natural product analogs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.8676
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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