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CS-W001157 4
Total: USD 88.00

Triphenylsulfonium chloride

  • CAS No. 4270-70-6

  • Cat. No. CS-0199130
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Triphenylsulfonium chloride|CS-0199130

Structure of 4270-70-6

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General Information

  • CAS No. 4270-70-6
  • Cat. No. CS-0199130
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₅ClS
  • Molecular Weight 298.83
  • Synonym(s) ’triphenylsulfoniumchloride’solution
  • SMILES C1=CC=C(C=C1)[S+](C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]

Description

Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Synthesis

  • Route1
    • In-stock
      Diphenyl sulfoxide|CS-W015498
      945-51-7
    • null|null
      100-59-4
    • ~%
    • In-stock
      Triphenylsulfonium chloride|CS-0199130
      4270-70-6

    References

    • SHIN-ETSU CHEMICAL CO., LTD. Patent: US2007/298352 A1, 2007 ; Location in patent: Page/Page column 27 ;
  • Route2

    References

    • Shin-Etsu Chemical Co., Ltd. Patent: US2002/77493 A1, 2002 ;
  • Route3
    • null|null
      108-90-7
    • ~%
    • In-stock
      Triphenylsulfonium chloride|CS-0199130
      4270-70-6

    References

    • Shin-Etsu Chemical Co., Ltd. Patent: EP1710230 A1, 2006 ; Location in patent: Page/Page column 31 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   1.786
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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