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Structure of 42599-26-8
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1-Methylpyrrolidine-2,3-dione delivers a highly reactive cyclic anhydride moiety ideal for amine coupling and protein modification. This bench-stable reagent features enhanced solubility in organic solvents and undergoes selective acylation under mild conditions. The methyl group confers improved stability without compromising reactivity, enabling efficient conjugation workflows in chemical biology and materials functionalization.
1-Methylpyrrolidine-2,3-dione serves as a versatile dienophile in Diels-Alder reactions and functions as a stable, bench-ready building block for heterocyclic synthesis. Its electron-deficient diene system enables efficient cycloadditions with a range of dienes, facilitating rapid access to complex carbocyclic and heterocyclic scaffolds. The molecule exhibits excellent functional group tolerance and is amenable to straightforward purification, making it a practical choice for synthetic organic chemists developing pharmaceutical intermediates and natural product analogs.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: