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Structure of 42521-10-8
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Methyl 2-chloro-6-methoxyisonicotinate features a pyridine core bearing ortho-chloro and para-methoxy substituents, enabling precise electronic tuning for cross-coupling reactions. This bench-stable ester integrates readily into synthetic sequences requiring electron-deficient heteroaryl building blocks.
Methyl 2-chloro-6-methoxyisonicotinate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. The ortho-chloro group facilitates palladium-catalyzed cross-coupling reactions, while the ester and methoxy functionalities offer orthogonal handles for further derivatization. Bench-stable and readily purified by flash chromatography, it functions reliably in standard synthetic workflows for API development and heterocycle functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: