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CS-W001157 4
Total: USD 88.00

4-Hydroxyhygric acid

  • CAS No. 4252-82-8

  • Cat. No. CS-0151198
  • Purity≥97%
  • MDL No.MFCD01632078
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Hydroxyhygric acid|CS-0151198

Structure of 4252-82-8

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Description

4-Hydroxyhygric acid is a bioactive phenolic compound featuring a hydroxyl group at the 4-position, enhancing its solubility and reactivity in aqueous environments. This derivative exhibits improved stability under standard bench conditions and serves as a key intermediate in the synthesis of natural product analogs and pharmaceutical candidates requiring precise oxygenation patterns.

Application

4-Hydroxyhygric acid serves as a valuable building block in the synthesis of complex natural product scaffolds, particularly those featuring substituted tetrahydrofuran cores. Its well-defined hydroxyl and carboxylic acid functionalities enable selective derivatization, including esterification and etherification, under standard organic conditions. The molecule exhibits good bench stability and facilitates efficient purification via standard chromatographic methods, making it suitable for iterative synthetic sequences in medicinal chemistry and process development workflows.

General Information

  • CAS No. 4252-82-8
  • Cat. No. CS-0151198
  • Purity ≥97%
  • MDL No. MFCD01632078
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₃
  • Molecular Weight 145.16
  • Synonym(s) None
  • SMILES CN1C[C@@H](C[C@H]1C(=O)O)O

Computational Chemistry Data

  • TPSA   60.77
  • LogP   -0.864
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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