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Structure of 42508-60-1
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This pyridinium salt features a reactive ketone-bearing side chain, enabling direct conjugation to nucleophiles under mild conditions. The electrophilic carbonyl group facilitates efficient Michael additions and enamine formation, making it valuable for synthetic transformations in medicinal chemistry and chemical biology workflows.
1-(2-Oxopropyl)pyridin-1-ium chloride serves as a versatile electrophilic acyl transfer reagent, enabling efficient α-acylation of enolizable carbonyl compounds and nucleophiles under mild conditions. Its pyridinium core provides excellent solubility and bench stability, while the ketone functionality offers compatibility with standard functional group manipulations. This reagent facilitates rapid access to β-keto carbonyl scaffolds commonly found in pharmaceutical intermediates and natural product syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: