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CS-W001157 4
Total: USD 88.00

(11bS)-N-(1-Phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine

  • CAS No. 422509-53-3

  • Cat. No. CS-W011615
  • Purity≥95%
  • MDL No.MFCD04117689

*For research and further manufacturing use only, not for direct human use.

(11bS)-N-(1-Phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine|CS-W011615

Structure of 422509-53-3

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General Information

  • CAS No. 422509-53-3
  • Cat. No. CS-W011615
  • Purity ≥95%
  • MDL No. MFCD04117689
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₂₂NO₂P
  • Molecular Weight 435.45
  • Synonym(s) (S)-(+)-(3,5-Dioxa-4-phospha-cyclohepta[2,1-a
  • SMILES CC(C1=CC=CC=C1)NP2OC3=[C@]([C@]4=C(C=CC=C5)C5=CC=C4O2)C6=C(C=CC=C6)C=C3

Application

(11bS)-N-(1-Phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine serves as a chiral phosphine ligand enabling efficient transition-metal-catalyzed cross-coupling reactions. Its rigid, polycyclic framework provides exceptional stereochemical control and thermal stability, while the amine functionality enhances solubility and coordination versatility. This ligand facilitates C–C and C–heteroatom bond formations under mild conditions with broad functional group tolerance, making it particularly valuable in asymmetric synthesis and catalytic process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.31
  • LogP   8.9011
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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