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Structure of 42205-73-2
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4-tert-Butylpyridine-2-carbonitrile features a sterically hindered tert-butyl group and an electron-deficient nitrile moiety positioned ortho to the pyridine nitrogen. This combination enhances its stability and modulates electronic properties, enabling effective coordination in catalytic systems. The molecule integrates readily into ligand frameworks for transition metal complexes.
4-tert-Butylpyridine-2-carbonitrile serves as a versatile building block in medicinal chemistry and catalysis, offering a robust pyridine scaffold with orthogonal functional handles. The tert-butyl group provides steric bulk and enhanced solubility, while the nitrile enables nucleophilic addition, imine formation, or conversion to amides and carboxylic acids. Its stability under standard reaction conditions facilitates efficient transformations in multistep syntheses and ligand development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: