Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2(1H)-pyridinone

  • CAS No. 4214-79-3

  • Cat. No. CS-W009538
  • Purity≥98%
  • MDL No.MFCD00006275

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2(1H)-pyridinone|CS-W009538

Structure of 4214-79-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 4214-79-3
  • Cat. No. CS-W009538
  • Purity ≥98%
  • MDL No. MFCD00006275
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄ClNO
  • Molecular Weight 129.54
  • Synonym(s) None
  • SMILES O=C1C=CC(Cl)=CN1

Description

5-Chloro-2(1H)-pyridinone is a bench-stable heterocyclic compound featuring a chlorine substituent at the 5-position and a lactam functionality at C2. This electron-deficient pyridinone scaffold serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules through nucleophilic substitution or transition-metal-catalyzed coupling reactions.

Application

5-Chloro-2(1H)-pyridinone serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles through nucleophilic substitution and coupling reactions. Its well-established reactivity at the C5 position facilitates functionalization under mild conditions, while the pyridinone core offers favorable solubility and metabolic stability. The compound exhibits excellent bench stability and is compatible with common protecting group strategies, making it ideal for modular synthesis workflows.

Synthesis

  • Route1
    • α-Pyridone Levetiracetam Impurity|CS-0213990
      142-08-5
    • ~60%
    • In-stock
      5-Chloro-2(1H)-pyridinone|CS-W009538
      4214-79-3

    References

    • Katritzky, Alan R.; Khan, Ghulam R.; Leahy, David E.; Rosa, Michael De Journal of Organic Chemistry, 1984 , vol. 49, # 25 p. 4784 - 4786
  • Route2

    References

    • Raghoottama, P. S.; Soundararajan, S.; Ramakrishna, J. Journal of Molecular Structure, 1987 , vol. 157, p. 371 - 384
  • Route3
    • null|null
      89478-74-0
    • ~0%
    • In-stock
      5-Chloro-2(1H)-pyridinone|CS-W009538
      4214-79-3
    • null|null
      89478-85-3

    References

    • Katritzky, Alan R.; Awartani, Radi Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2623 - 2627

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   32.86
  • LogP   1.0283
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-2(1H)-pyridinone sigma5-Chloro-2(1H)-pyridinone manufacturer5-Chloro-2(1H)-pyridinone price5-Chloro-2(1H)-pyridinone structure5-Chloro-2(1H)-pyridinone SDSbuy 5-Chloro-2(1H)-pyridinone5-Chloro-2(1H)-pyridinone supplier5-Chloro-2(1H)-pyridinone uses5-Chloro-2(1H)-pyridinone molecular weightprice of 5-Chloro-2(1H)-pyridinone5-Chloro-2(1H)-pyridinone chemical name formula of 5-Chloro-2(1H)-pyridinone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label