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CS-W001157 4
Total: USD 88.00

(E)-Ethyl cinnamate

  • CAS No. 4192-77-2

  • Cat. No. CS-0356392
  • Purity≥97%
  • MDL No.MFCD00009189

*For research and further manufacturing use only, not for direct human use.

(E)-Ethyl cinnamate|CS-0356392

Structure of 4192-77-2

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General Information

  • CAS No. 4192-77-2
  • Cat. No. CS-0356392
  • Purity ≥97%
  • MDL No. MFCD00009189
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₂
  • Molecular Weight 176.21
  • Synonym(s) None
  • SMILES O=C(OCC)/C=C/C1=CC=CC=C1

Description

(E)-Ethyl cinnamate is a bench-stable, moisture-tolerant ester featuring a conjugated trans-alkene and a phenylacrylate backbone. This configuration delivers enhanced photostability and predictable reactivity in synthetic transformations. The ethyl ester group enables straightforward derivatization while maintaining compatibility with standard organic reaction conditions.

Application

(E)-Ethyl cinnamate serves as a versatile synthetic building block for styryl-containing compounds, enabling efficient access to conjugated systems via standard cross-coupling and cycloaddition reactions. Its bench-stable nature and predictable (E)-configuration facilitate reproducible transformations in medicinal chemistry and materials synthesis.

Synthesis

  • Route1
    • null|null
      108-90-7
    • null|null
      140-88-5
    • ~92%
    • In-stock
      (E)-Ethyl cinnamate|CS-0356392
      4192-77-2

    References

    • Lee, Dong-Hwan; Taher, Abu; Hossain, Shahin; Jin, Myung-Jong Organic Letters, 2011 , vol. 13, # 20 p. 5540 - 5543
  • Route2
    • null|null
      100-52-7
    • null|null
      141-78-6
    • ~97%
    • In-stock
      (E)-Ethyl cinnamate|CS-0356392
      4192-77-2

    References

    • Augustine, John Kallikat; Boodappa, Chandrakantha; Venkatachaliah, Srinivasa; Mariappan, Ayyampillai Tetrahedron Letters, 2014 , vol. 55, # 24 p. 3503 - 3506
  • Route3
    • In-stock
      trans-Cinnamaldehyde|CS-0031318
      14371-10-9
    • null|null
      64-17-5
    • ~98%
    • In-stock
      (E)-Ethyl cinnamate|CS-0356392
      4192-77-2

    References

    • De Sarkar, Suman; Grimme, Stefan; Studer, Armido Journal of the American Chemical Society, 2010 , vol. 132, p. 1190 - 1191

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.2629
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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