Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Methoxy-4-(methylsulfonyl)aniline

  • CAS No. 41608-73-5

  • Cat. No. CS-W006498
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-4-(methylsulfonyl)aniline|CS-W006498

Structure of 41608-73-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 41608-73-5
  • Cat. No. CS-W006498
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₃S
  • Molecular Weight 201.24
  • Synonym(s) 4-Methanesulfonyl-2-Methoxyaniline
  • SMILES NC1=CC=C(S(=O)(C)=O)C=C1OC

Description

2-Methoxy-4-(methylsulfonyl)aniline features a methoxy group at the ortho position and a methylsulfonyl moiety at the para position relative to the amino group. This electron-withdrawing sulfone enhances stability while maintaining solubility in polar solvents. The compound serves as a key intermediate in the synthesis of functional dyes, agrochemicals, and pharmaceuticals requiring tailored electronic properties and metabolic resistance.

Application

2-Methoxy-4-(methylsulfonyl)aniline serves as a versatile building block in medicinal chemistry, enabling efficient access to diverse heterocyclic scaffolds. Its ortho-methoxy and para-methylsulfonyl substituents provide orthogonal functional handles for late-stage modification, while the aniline core offers reliable reactivity in Suzuki-Miyaura coupling and electrophilic substitution. Bench-stable and amenable to straightforward purification, it functions effectively in multi-step syntheses requiring high functional group tolerance.

Synthesis

  • Route1

    References

    • F. HOFFMANN-LA ROCHE AG; BAKER-GLENN, Charles; CHAMBERS, Mark; CHAN, Bryan K.; CHEN, Huifen; ESTRADA, Anthony; SHORE, Daniel; SWEENEY, Zachary Patent: WO2013/79493 A1, 2013 ;
  • Route2

    References

    • F. HOFFMANN-LA ROCHE AG; BAKER-GLENN, Charles; CHAMBERS, Mark; CHAN, Bryan K.; CHEN, Huifen; ESTRADA, Anthony; SHORE, Daniel; SWEENEY, Zachary Patent: WO2013/79493 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   69.39
  • LogP   0.6809
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Methoxy-4-(methylsulfonyl)aniline sigma2-Methoxy-4-(methylsulfonyl)aniline manufacturer2-Methoxy-4-(methylsulfonyl)aniline price2-Methoxy-4-(methylsulfonyl)aniline structure2-Methoxy-4-(methylsulfonyl)aniline SDSbuy 2-Methoxy-4-(methylsulfonyl)aniline2-Methoxy-4-(methylsulfonyl)aniline supplier2-Methoxy-4-(methylsulfonyl)aniline uses2-Methoxy-4-(methylsulfonyl)aniline molecular weightprice of 2-Methoxy-4-(methylsulfonyl)aniline2-Methoxy-4-(methylsulfonyl)aniline chemical name formula of 2-Methoxy-4-(methylsulfonyl)aniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label