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Structure of 41492-05-1
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1-Bromo-4-butylbenzene features a butyl chain appended to a para-brominated benzene ring, delivering enhanced lipophilicity and structural rigidity. This configuration enables efficient incorporation into cross-coupling reactions, particularly Suzuki-Miyaura processes, where the bromine serves as a reliable coupling handle. The molecule exhibits excellent stability under standard conditions and facilitates the construction of complex aromatic architectures in synthetic workflows.
1-Bromo-4-butylbenzene serves as a versatile aryl halide building block in cross-coupling reactions, enabling efficient C–C bond formation via palladium-catalyzed methodologies. The butyl substituent provides favorable lipophilicity and steric profile for downstream applications in medicinal chemistry and materials science. Bench-stable and readily purified by distillation or chromatography, it exhibits excellent functional group tolerance and compatibility with standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS05,GHS09
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Signal Word : Danger
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UN#: 3082
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H410
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Precautionary Statements : P264-P273-P280-P302+P352-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: