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CS-W001157 4
Total: USD 88.00

1-(tert-Butyl)-1H-pyrrole-2,5-dione

  • CAS No. 4144-22-3

  • Cat. No. CS-W021263
  • Purity≥98%
  • MDL No.MFCD00191885

*For research and further manufacturing use only, not for direct human use.

1-(tert-Butyl)-1H-pyrrole-2,5-dione|CS-W021263

Structure of 4144-22-3

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General Information

  • CAS No. 4144-22-3
  • Cat. No. CS-W021263
  • Purity ≥98%
  • MDL No. MFCD00191885
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₂
  • Molecular Weight 153.18
  • Synonym(s) N-tert-Butylmaleimide
  • SMILES O=C(C=C1)N(C(C)(C)C)C1=O

Description

1-(tert-Butyl)-1H-pyrrole-2,5-dione features a sterically hindered tert-butyl group that enhances stability and solubility in organic media. This electron-deficient dienophile integrates readily into Diels-Alder reactions under mild conditions, offering high regioselectivity and clean adduct formation.

Synthesis

  • Route1
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      32350-46-2
    • ~71%
    • In-stock
      1-(tert-Butyl)-1H-pyrrole-2,5-dione|CS-W021263
      4144-22-3

    References

    • Wang, Z. Y. Synthetic Communications, 1990 , vol. 20, # 11 p. 1607 - 1610
  • Route2
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      134276-00-9
    • ~%
    • In-stock
      1-(tert-Butyl)-1H-pyrrole-2,5-dione|CS-W021263
      4144-22-3

    References

    • Salewska, Natalia; Boros-Majewska, Joanna; Lcka, Izabela; Chylinska, Katarzyna; Sabisz, Michal; Milewski, Slawomir; Milewska, Maria J. Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 1 p. 117 - 124
  • Route3
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      108-31-6
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      75-64-9
    • ~%
    • In-stock
      1-(tert-Butyl)-1H-pyrrole-2,5-dione|CS-W021263
      4144-22-3

    References

    • Mloston; Janicka; Woznicka; Linden; Heimgartner Polish Journal of Chemistry, 2003 , vol. 77, # 12 p. 1805 - 1817

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.38
  • LogP   0.7099
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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