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Structure of 4137-56-8
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Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside serves as a key chiral synthon in nucleoside synthesis, featuring a protected ribose scaffold with orthogonal functional handles. The isopropylidene group stabilizes the 2',3'-diol moiety, while the tosyl ester at the 5'-position enables selective transformations. This configuration supports efficient glycosylation and downstream derivatization under standard conditions.
Methyl 2,3-O-isopropylidene-5-O-tosyl-D-ribonucleoside serves as a versatile building block in nucleoside synthesis, offering orthogonal protection for the ribose hydroxyls. The isopropylidene group stabilizes the 2',3'-diol during transformations, while the tosyl moiety provides a robust leaving group for displacement reactions. This derivative exhibits excellent bench stability and facilitates efficient glycosylation, coupling, and functionalization steps critical to constructing complex nucleoside analogs and heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: