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CS-W001157 4
Total: USD 88.00

4-(4-Methylphenoxy)aniline

  • CAS No. 41295-20-9

  • Cat. No. CS-0117157
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(4-Methylphenoxy)aniline|CS-0117157

Structure of 41295-20-9

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General Information

  • CAS No. 41295-20-9
  • Cat. No. CS-0117157
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃NO
  • Molecular Weight 199.25
  • Synonym(s) 4-Aminophenyl p-Tolyl Ether
  • SMILES NC1=CC=C(OC2=CC=C(C)C=C2)C=C1

Description

4-(4-Methylphenoxy)aniline features a phenolic ether linkage fused to an aromatic amine, delivering enhanced solubility and thermal stability. This structure integrates electron-donating methyl and amino groups, enabling efficient coupling in pharmaceutical intermediates and advanced materials synthesis under standard conditions.

Application

4-(4-Methylphenoxy)aniline serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient construction of biaryl ether scaffolds. Its phenolic oxygen facilitates electrophilic substitution and coupling reactions, while the aniline nitrogen supports derivatization via acylation or diazotization. The molecule exhibits good bench stability and is readily purified by recrystallization, making it suitable for scale-up in process chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   3.36952
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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