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CS-W001157 4
Total: USD 88.00

1H-Benzimidazol-5-ol

  • CAS No. 41292-65-3

  • Cat. No. CS-W001209
  • Purity≥96%
  • MDL No.MFCD02241303

*For research and further manufacturing use only, not for direct human use.

1H-Benzimidazol-5-ol|CS-W001209

Structure of 41292-65-3

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General Information

  • CAS No. 41292-65-3
  • Cat. No. CS-W001209
  • Purity ≥96%
  • MDL No. MFCD02241303
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O
  • Molecular Weight None
  • Synonym(s) 5-Hydroxybenzimidazole
  • SMILES OC1=CC=C2N=CNC2=C1

Description

1H-Benzimidazol-5-ol features a fused benzene-imidazole core with a phenolic hydroxyl at the 5-position, conferring enhanced solubility and hydrogen-bonding capacity. This scaffold serves as a key pharmacophore in kinase inhibitors and fluorescent probes, offering stability under standard conditions and compatibility with diverse synthetic transformations.

Application

1H-Benzimidazol-5-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its phenolic hydroxyl group facilitates direct functionalization and conjugation, while the imidazole core exhibits favorable solubility and stability under standard synthetic conditions. The compound functions effectively in coupling reactions and acts as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.2685
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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