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CS-W001157 4
Total: USD 88.00

H-Asp-OtBu

  • CAS No. 4125-93-3

  • Cat. No. CS-W006400
  • Purity≥98%
  • MDL No.MFCD00171675

*For research and further manufacturing use only, not for direct human use.

H-Asp-OtBu|CS-W006400

Structure of 4125-93-3

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General Information

  • CAS No. 4125-93-3
  • Cat. No. CS-W006400
  • Purity ≥98%
  • MDL No. MFCD00171675
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅NO₄
  • Molecular Weight 189.21
  • Synonym(s) None
  • SMILES OC(C[C@H](N)C(OC(C)(C)C)=O)=O

Description

H-Asp-OtBu serves as a protected aspartic acid building block for peptide synthesis, featuring a tert-butyl ester that enables straightforward deprotection under mild acidic conditions. This stable, bench-ready derivative simplifies incorporation into oligopeptide chains while minimizing side reactions during coupling steps.

Application

H-Asp-OtBu serves as a key building block in peptide synthesis, offering a readily accessible source of protected aspartic acid for the construction of biologically relevant sequences. The OtBu (tert-butyl) ester group provides excellent stability under standard coupling conditions and facilitates straightforward deprotection via mild acid treatment. Its well-documented compatibility with common solid-phase and solution-phase protocols enables efficient incorporation into target peptides without side reactions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   89.62
  • LogP   0.1301
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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