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Structure of 412003-95-3
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2,4-Dimethylpyrimidin-5-ol features a pyrimidine core bearing methyl groups at positions 2 and 4, enhancing steric protection of the C5 hydroxyl. This bench-stable derivative exhibits improved solubility in organic solvents compared to unsubstituted analogs, enabling straightforward incorporation into synthetic sequences. The hydroxyl group serves as a versatile handle for derivatization, facilitating coupling reactions under mild conditions. Its electron-rich character supports efficient metal-catalyzed transformations, making it a valuable scaffold in medicinal chemistry and materials synthesis.
2,4-Dimethylpyrimidin-5-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its stability under standard reaction conditions and compatibility with common coupling protocols facilitate downstream functionalization. The molecule functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive heterocycles, offering predictable reactivity and straightforward purification.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: