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Structure of 4108-90-1
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Piperidine-1-sulfonamide features a sulfonamide group attached to the nitrogen atom of a piperidine ring, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, serving as a key heterocyclic motif for optimizing pharmacokinetic profiles in bioactive compounds.
Piperidine-1-sulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and electrophilic substitution reactions. Its sulfonamide group exhibits good bench stability and facilitates hydrogen bonding interactions in target binding sites. The molecule functions effectively in multi-step syntheses due to its functional group tolerance and ease of purification, making it a practical choice for scaffold diversification in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: