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Structure of 4102-53-8
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4-Iodo-2,6-dimethylaniline features a sterically hindered aromatic core with electron-donating methyl groups flanking a reactive iodo substituent. This configuration enhances stability and directs regioselective coupling in cross-coupling reactions. The compound serves as a robust building block for pharmaceutical intermediates and functional materials, offering predictable reactivity under standard conditions.
4-Iodo-2,6-dimethylaniline serves as a valuable building block in the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its ortho-dimethyl substitution enhances stability and modulates reactivity, while the iodine handle enables reliable Suzuki-Miyaura and Stille coupling reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: