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Structure of 408523-59-1
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2,4-Dichloro-6-nitroquinoline features a rigid quinoline core bearing two chlorine substituents and a nitro group at the 6-position, creating a highly electron-deficient heterocycle. This structural configuration enhances its utility in transition metal-catalyzed cross-coupling reactions and as a fluorophore scaffold in probe development. The molecule exhibits robust stability under standard bench conditions and demonstrates favorable solubility in common organic solvents.
2,4-Dichloro-6-nitroquinoline serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted quinoline scaffolds through palladium-catalyzed cross-coupling reactions. The dichloro and nitro substituents provide orthogonal reactivity for sequential functionalization, while the molecule exhibits good bench stability and ease of purification—key attributes for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: