6-bromo-2-methylimidazo[1,2-a]pyridine

Name: 6-bromo-2-methylimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 4044-99-9
Cat. No. CS-W000534
Purity≥97%
MDL No.MFCD09800594

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-bromo-2-methylimidazo[1,2-a]pyridine|CS-W000534

Structure of 4044-99-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 4044-99-9
Cat. No. CS-W000534
Purity ≥97%
MDL No. MFCD09800594
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) None
SMILES Cc1cn2cc(Br)ccc2n1

Description

6-Bromo-2-methylimidazo[1,2-a]pyridine is a heterocyclic scaffold featuring a brominated imidazo[1,2-a]pyridine core with a methyl group at the 2-position. This electron-deficient system enables efficient coupling reactions in cross-coupling and transition-metal-catalyzed transformations. The bromine atom serves as a reactive handle for C–C and C–heteroatom bond formation, while the methyl substituent enhances solubility and steric profile. This compound functions as a key building block in medicinal chemistry and materials science applications.

Application

6-Bromo-2-methylimidazo[1,2-a]pyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the bromine site via Pd-catalyzed cross-coupling reactions. The methyl group enhances solubility and modulates electronic properties, while the imidazo[1,2-a]pyridine core provides structural rigidity and hydrogen-bonding capacity. This scaffold exhibits excellent bench stability and compatibility with standard reaction conditions, facilitating efficient synthesis of complex heterocyclic compounds relevant to kinase inhibitor development and CNS-targeted therapeutics.

Synthesis

Route1
- In-stock
  
  1072-97-5
- 78-95-5
- ~18%
- In-stock
  
  4044-99-9
References
- Chytil, Milan; Engel, Sharon R.; Fang, Qun Kevin; Spear, Kerry L. Patent: US2010/204214 A1, 2010 ; Location in patent: Page/Page column 112 ;
Route2
- In-stock
  
  1072-97-5
- 598-31-2
- ~%
- In-stock
  
  4044-99-9
References
- Campbell; McCall Journal of the Chemical Society, 1951 , p. 2411,2415 Full Text Show Details Takahashi; Numata Yakugaku Zasshi, 1946 , vol. 66, p. Ausg. B, S. 75 Chem.Abstr., 1952 , p. 112

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

6-bromo-2-methylimidazo[1,2-a]pyridine sigma6-bromo-2-methylimidazo[1,2-a]pyridine manufacturer6-bromo-2-methylimidazo[1,2-a]pyridine price6-bromo-2-methylimidazo[1,2-a]pyridine structure6-bromo-2-methylimidazo[1,2-a]pyridine SDSbuy 6-bromo-2-methylimidazo[1,2-a]pyridine6-bromo-2-methylimidazo[1,2-a]pyridine supplier6-bromo-2-methylimidazo[1,2-a]pyridine uses6-bromo-2-methylimidazo[1,2-a]pyridine molecular weightprice of 6-bromo-2-methylimidazo[1,2-a]pyridine6-bromo-2-methylimidazo[1,2-a]pyridine chemical name formula of 6-bromo-2-methylimidazo[1,2-a]pyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-bromo-2-methylimidazo[1,2-a]pyridine

CAS No. 4044-99-9

Recommended Products