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CS-W001157 4
Total: USD 88.00

(3-Fluorophenoxy)acetic acid

  • CAS No. 404-98-8

  • Cat. No. CS-W002938
  • Purity≥98%
  • MDL No.MFCD02295721

*For research and further manufacturing use only, not for direct human use.

(3-Fluorophenoxy)acetic acid|CS-W002938

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General Information

  • CAS No. 404-98-8
  • Cat. No. CS-W002938
  • Purity ≥98%
  • MDL No. MFCD02295721
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO₃
  • Molecular Weight None
  • Synonym(s) (3-Fluoro-phenoxy)-acetic acid
  • SMILES FC1=CC(OCC(O)=O)=CC=C1

Description

(3-Fluorophenoxy)acetic acid features a fluorinated aromatic ring coupled to a carboxylic acid-bearing aliphatic chain, enabling enhanced metabolic stability and improved membrane permeability. This structural motif facilitates integration into bioactive molecules where controlled lipophilicity and targeted delivery are critical.

Application

(3-Fluorophenoxy)acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through established esterification, amidation, and Suzuki coupling protocols. Its ortho-fluoro substitution enhances metabolic stability and modulates electronic properties, while the carboxylic acid functionality offers direct handle for conjugation. Bench-stable and readily purified by recrystallization, it functions reliably in standard peptide and heterocycle assembly workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.2891
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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