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Structure of 403660-57-1
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5-Ethynyl-1H-indazole is a bench-stable, electron-deficient heterocycle featuring a terminal alkyne group poised for Cu-catalyzed coupling reactions. This functionalized indazole integrates efficiently into bioconjugation workflows and serves as a key scaffold in the synthesis of kinase inhibitors and fluorescent probes.
5-Ethynyl-1H-indazole serves as a versatile building block in medicinal chemistry, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for triazole formation. Its terminal alkyne functionality exhibits excellent stability under standard bench conditions and tolerates diverse functional groups, facilitating straightforward conjugation and late-stage diversification in target molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: