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CS-W001157 4
Total: USD 88.00

(S)-2-Phenylsuccinic acid

  • CAS No. 4036-30-0

  • Cat. No. CS-W010661
  • Purity≥97%
  • MDL No.MFCD00065929

*For research and further manufacturing use only, not for direct human use.

(S)-2-Phenylsuccinic acid|CS-W010661

Structure of 4036-30-0

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General Information

  • CAS No. 4036-30-0
  • Cat. No. CS-W010661
  • Purity ≥97%
  • MDL No. MFCD00065929
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₄
  • Molecular Weight 194.18
  • Synonym(s) (S)-Phenylsuccinic acid
  • SMILES O=C(O)[C@H](C1=CC=CC=C1)CC(O)=O

Description

(S)-2-Phenylsuccinic acid is a chiral dicarboxylic acid featuring a stereogenic center at the 2-position, flanked by a phenyl group and two carboxylate moieties. This configuration imparts distinct reactivity in asymmetric synthesis, enabling selective derivatization for chiral auxiliaries or catalysts. The molecule exhibits enhanced solubility in polar solvents and stability under standard bench conditions, facilitating handling in process development workflows.

Application

(S)-2-Phenylsuccinic acid serves as a valuable chiral building block in asymmetric synthesis, enabling the stereoselective construction of pharmaceutical intermediates and bioactive molecules. Its well-defined stereochemistry and bench-stable crystalline form facilitate purification and handling, while its dicarboxylic acid functionality supports diverse derivatization pathways including esterification, amide formation, and metal complexation for catalytic applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   1.3295
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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