Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1H-Indole, 6-fluoro-2-methyl-

  • CAS No. 40311-13-5

  • Cat. No. CS-0027056
  • Purity≥97%
  • MDL No.MFCD09027714
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1H-Indole, 6-fluoro-2-methyl-|CS-0027056

Structure of 40311-13-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

6-Fluoro-2-methyl-1H-indole is a fluorinated indole scaffold featuring a methyl group at the 2-position and a fluoro substituent at the 6-position, conferring enhanced metabolic stability and altered electronic properties. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and CNS-targeted therapeutics. The fluorine atom improves membrane permeability and modulates pKa, while the methyl group provides steric control during coupling reactions. Its bench-stable nature enables reliable handling under standard conditions.

Application

6-Fluoro-2-methyl-1H-indole serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard electrophilic substitution and transition-metal-catalyzed coupling reactions. The fluorine at the 6-position enhances metabolic stability and modulates electronic properties, while the methyl group provides a site for further functionalization. Its bench-stable nature and compatibility with common reaction conditions facilitate efficient synthesis of indole-based scaffolds relevant to pharmaceutical development.

General Information

  • CAS No. 40311-13-5
  • Cat. No. CS-0027056
  • Purity ≥97%
  • MDL No. MFCD09027714
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈FN
  • Molecular Weight 149.16
  • Synonym(s) 6-FLUORO-2-METHYLINDOLE
  • SMILES CC(N1)=CC2=C1C=C(F)C=C2

Computational Chemistry Data

  • TPSA   15.79
  • LogP   2.61542
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1H-Indole, 6-fluoro-2-methyl- sigma1H-Indole, 6-fluoro-2-methyl- manufacturer1H-Indole, 6-fluoro-2-methyl- price1H-Indole, 6-fluoro-2-methyl- structure1H-Indole, 6-fluoro-2-methyl- SDSbuy 1H-Indole, 6-fluoro-2-methyl-1H-Indole, 6-fluoro-2-methyl- supplier1H-Indole, 6-fluoro-2-methyl- uses1H-Indole, 6-fluoro-2-methyl- molecular weightprice of 1H-Indole, 6-fluoro-2-methyl-1H-Indole, 6-fluoro-2-methyl- chemical name formula of 1H-Indole, 6-fluoro-2-methyl-
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label