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CS-W001157 4
Total: USD 88.00

1,5-Dihydro-2H-pyrrol-2-one

  • CAS No. 4031-15-6

  • Cat. No. CS-0135756
  • Purity≥90%
  • MDL No.MFCD06658513

*For research and further manufacturing use only, not for direct human use.

1,5-Dihydro-2H-pyrrol-2-one|CS-0135756

Structure of 4031-15-6

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General Information

  • CAS No. 4031-15-6
  • Cat. No. CS-0135756
  • Purity ≥90%
  • MDL No. MFCD06658513
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅NO
  • Molecular Weight 83.09
  • Synonym(s) 3-Pyrrolin-2-one
  • SMILES O=C1NCC=C1

Application

1,5-Dihydro-2H-pyrrol-2-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyrrolidine derivatives and heterocyclic scaffolds. Its enamide functionality facilitates conjugate additions, cycloadditions, and transition-metal-catalyzed transformations. The compound exhibits good bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step syntheses.

Synthesis

  • Route1
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      109-97-7
    • ~54%
    • In-stock
      1,5-Dihydro-2H-pyrrol-2-one|CS-0135756
      4031-15-6

    References

    • Onkenhout, W.; Koeveringe, J. A. van; Lugtenburg, J. Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 3 p. 106 - 109
  • Route2

    References

    • Koltunov, Konstantin Yu.; Prakash, G. K. Surya; Rasul, Golam; Olah, George A. European Journal of Organic Chemistry, 2006 , # 21 p. 4861 - 4866
  • Route3
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      54238-27-6
    • ~%
    • In-stock
      1,5-Dihydro-2H-pyrrol-2-one|CS-0135756
      4031-15-6

    References

    • Langenbeck; Boser Chemische Berichte, 1951 , vol. 84, p. 526

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   -0.3276
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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