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CS-W001157 4
Total: USD 88.00

6-(4-Morpholinyl)pyrazine-2-carboxylic acid

  • CAS No. 40262-73-5

  • Cat. No. CS-W008712
  • Purity≥98%
  • MDL No.MFCD00233274

*For research and further manufacturing use only, not for direct human use.

6-(4-Morpholinyl)pyrazine-2-carboxylic acid|CS-W008712

Structure of 40262-73-5

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General Information

  • CAS No. 40262-73-5
  • Cat. No. CS-W008712
  • Purity ≥98%
  • MDL No. MFCD00233274
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N₃O₃
  • Molecular Weight 209.20
  • Synonym(s) 6-morpholinopyrazine-2-carboxylic acid
  • SMILES O=C(C1=NC(N2CCOCC2)=CN=C1)O

Description

6-(4-Morpholinyl)pyrazine-2-carboxylic acid features a pyrazine core functionalized with a morpholine ring at the 6-position and a carboxylic acid group at the 2-position, delivering enhanced solubility and hydrogen-bonding capacity. This combination enables efficient integration into bioactive scaffolds for medicinal chemistry applications.

Application

6-(4-Morpholinyl)pyrazine-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of pyrazine-based scaffolds through standard amide coupling and electrophilic substitution reactions. Its carboxylic acid functionality facilitates direct conjugation or derivatization, while the morpholinyl group enhances solubility and provides a handle for further functionalization. The compound exhibits bench stability and compatibility with common synthetic protocols, making it suitable for iterative synthesis campaigns targeting kinase inhibitors and other bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.55
  • LogP   0.0114
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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