1-(3-Bromo-4-methylphenyl)ethan-1-one

Name: 1-(3-Bromo-4-methylphenyl)ethan-1-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 40180-80-1
Cat. No. CS-0099378
Purity≥97%
MDL No.MFCD02683854

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(3-Bromo-4-methylphenyl)ethan-1-one|CS-0099378

Structure of 40180-80-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-(3-Bromo-4-methylphenyl)ethan-1-one features a brominated aromatic ring fused to a ketone-bearing ethyl side chain, delivering a sterically accessible platform for cross-coupling reactions. The para-methyl group enhances electron density at the ring, while the ortho-bromo substituent enables selective functionalization under palladium catalysis. This structure combines synthetic robustness with high reactivity in transition metal-mediated transformations.

Application

1-(3-Bromo-4-methylphenyl)ethan-1-one serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient Suzuki-Miyaura and Negishi couplings due to its stable aryl bromide and ketone functionalities. The methyl group enhances lipophilicity and metabolic stability, while the ketone facilitates downstream transformations such as reductive amination or enolization. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses of heterocyclic scaffolds and functionalized biaryls.

General Information

CAS No. 40180-80-1
Cat. No. CS-0099378
Purity ≥97%
MDL No. MFCD02683854
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₉BrO
Molecular Weight 213.07
Synonym(s) 3'-Bromo-4'-methylacetophenone
SMILES CC(C1=CC=C(C(Br)=C1)C)=O

Computational Chemistry Data

TPSA 17.07
LogP 2.96012
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1-(3-Bromo-4-methylphenyl)ethan-1-one sigma1-(3-Bromo-4-methylphenyl)ethan-1-one manufacturer1-(3-Bromo-4-methylphenyl)ethan-1-one price1-(3-Bromo-4-methylphenyl)ethan-1-one structure1-(3-Bromo-4-methylphenyl)ethan-1-one SDSbuy 1-(3-Bromo-4-methylphenyl)ethan-1-one1-(3-Bromo-4-methylphenyl)ethan-1-one supplier1-(3-Bromo-4-methylphenyl)ethan-1-one uses1-(3-Bromo-4-methylphenyl)ethan-1-one molecular weightprice of 1-(3-Bromo-4-methylphenyl)ethan-1-one1-(3-Bromo-4-methylphenyl)ethan-1-one chemical name formula of 1-(3-Bromo-4-methylphenyl)ethan-1-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(3-Bromo-4-methylphenyl)ethan-1-one

CAS No. 40180-80-1

Recommended Products