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CS-W001157 4
Total: USD 88.00

5-(4-Chlorophenyl)thiophene-2-carboxylic acid

  • CAS No. 40133-14-0

  • Cat. No. CS-0206166
  • Purity≥98%
  • MDL No.MFCD00206435

*For research and further manufacturing use only, not for direct human use.

5-(4-Chlorophenyl)thiophene-2-carboxylic acid|CS-0206166

Structure of 40133-14-0

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General Information

  • CAS No. 40133-14-0
  • Cat. No. CS-0206166
  • Purity ≥98%
  • MDL No. MFCD00206435
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇ClO₂S
  • Molecular Weight 238.69
  • Synonym(s) None
  • SMILES C1=CC(=CC=C1C2=CC=C(C(=O)O)S2)Cl

Synthesis

  • Route1
    • Ethyl 5-(4-chlorophenyl)thiophene-2-carboxylate|CS-0576288
      19282-40-7
    • ~94%
    • 5-(4-Chlorophenyl)thiophene-2-carboxylic acid|CS-0206166
      40133-14-0

    References

    • Bristol-Myers Squibb Company Patent: US2008/269110 A1, 2008 ; Location in patent: Page/Page column 18 ; US 20080269110 A1
  • Route2
    • null|null
      124-38-9
    • 2-(4-Chlorophenyl)thiophene|CS-0575318
      40133-23-1
    • ~74%
    • 5-(4-Chlorophenyl)thiophene-2-carboxylic acid|CS-0206166
      40133-14-0

    References

    • Nemoto, Koji; Onozawa, Satoru; Konno, Megumi; Morohashi, Naoya; Hattori, Tetsutaro Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 3 p. 369 - 371
  • Route3
    • 5-(4-Chlorophenyl)thiophene-2-carbaldehyde|CS-0308949
      38401-71-7
    • ~87%
    • 5-(4-Chlorophenyl)thiophene-2-carboxylic acid|CS-0206166
      40133-14-0

    References

    • Noguchi, Toshiya; Hasegawa, Masahiro; Tomisawa, Kazuyuki; Mitsukuchi, Morihiro Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4729 - 4742

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.7667
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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