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CS-W001157 4
Total: USD 88.00

H-cis-Hyp-OMe hydrochloride

  • CAS No. 40126-30-5

  • Cat. No. CS-W017145
  • Purity≥97%
  • MDL No.MFCD00237835

*For research and further manufacturing use only, not for direct human use.

H-cis-Hyp-OMe hydrochloride|CS-W017145

Structure of 40126-30-5

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General Information

  • CAS No. 40126-30-5
  • Cat. No. CS-W017145
  • Purity ≥97%
  • MDL No. MFCD00237835
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₃
  • Molecular Weight 181.62
  • Synonym(s) None
  • SMILES O=C([C@H]1NC[C@@H](O)C1)OC.Cl

Description

H-cis-Hyp-OMe (hydrochloride) features a stabilized cis-configured hypusine derivative with methyl ester protection, enabling direct incorporation into peptide sequences under standard coupling conditions. This bench-stable reagent facilitates efficient synthesis of bioactive peptides containing the post-translationally modified hypusine residue, offering enhanced solubility and compatibility in aqueous and organic solvent systems.

Application

H-cis-Hyp-OMe (hydrochloride) serves as a conformationally restricted proline analog, enabling the stabilization of bioactive peptide conformations through cis-proline-like geometry. Its methyl ester functionality provides enhanced solubility and facilitates downstream derivatization, while the hydrochloride salt ensures bench stability and ease of handling in solid-phase and solution-phase peptide synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.696
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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