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Structure of 400-98-6
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2-Nitro-4-(trifluoromethyl)aniline features a para-nitro group and a trifluoromethyl substituent on the aromatic ring, delivering enhanced electron deficiency and metabolic stability. This combination enables efficient incorporation into pharmaceutical intermediates and functional materials. The compound exhibits robust bench stability and facilitates direct coupling reactions under standard conditions.
2-Nitro-4-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized aromatic scaffolds. Its dual electron-withdrawing nitro and trifluoromethyl groups enhance reactivity in nucleophilic substitution and facilitate directed metalation. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for multi-step synthetic sequences requiring precise functional group placement.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: