Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Indoline-3-carboxylic acid

  • CAS No. 39891-70-8

  • Cat. No. CS-0139342
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Indoline-3-carboxylic acid|CS-0139342

Structure of 39891-70-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 39891-70-8
  • Cat. No. CS-0139342
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO₂
  • Molecular Weight 163.17
  • Synonym(s) Acide 2,3-dihydro-1H-indole-3-carboxylique
  • SMILES O=C(C1CNC2=C1C=CC=C2)O

Description

Indoline-3-carboxylic acid features a rigid, fused heterocyclic core with a pendant carboxylic acid group, enabling direct integration into peptide mimetics and bioactive scaffolds. The molecule exhibits enhanced metabolic stability and favorable solubility profiles under physiological conditions, facilitating its use in medicinal chemistry campaigns targeting CNS disorders and kinase inhibition.

Application

Indoline-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its fused indoline core offers structural rigidity and favorable pharmacokinetic properties, while the carboxylic acid group facilitates direct derivatization via amide coupling, esterification, or activation for cross-coupling reactions. The molecule exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for iterative synthesis in drug discovery campaigns.

Synthesis

  • Route1

    References

    • Reid, Mark; Carlyle, Ian; Caulfield, Wilson L.; Clarkson, Tom R.; Cusick, Fiona; Epemolu, Ola; Gilfillan, Robert; Goodwin, Richard; Jaap, David; O'Donnell, Elise C.; Presland, Jeremy; Rankovic, Zoran; Spinks, Daniel; Spinks, Gayle; Thomson, Anne M.; Thomson, Fiona; Strain, James; Wishart, Grant Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 12 p. 3713 - 3716

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   49.33
  • LogP   1.2803
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Indoline-3-carboxylic acid sigmaIndoline-3-carboxylic acid manufacturerIndoline-3-carboxylic acid priceIndoline-3-carboxylic acid structureIndoline-3-carboxylic acid SDSbuy Indoline-3-carboxylic acidIndoline-3-carboxylic acid supplierIndoline-3-carboxylic acid usesIndoline-3-carboxylic acid molecular weightprice of Indoline-3-carboxylic acidIndoline-3-carboxylic acid chemical name formula of Indoline-3-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label