6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine

Name: 6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine
Brand: ChemScene
Availability: InStock
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CAS No. 39824-26-5
Cat. No. CS-W000282
Purity≥97%
MDL No.MFCD03788833

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine|CS-W000282

Structure of 39824-26-5

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Description

6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine features a protected ribose moiety that enhances stability and facilitates controlled incorporation into nucleic acid analogs. The chlorinated purine base supports efficient coupling in oligonucleotide synthesis workflows, offering improved resistance to hydrolysis under standard conditions.

Application

6-Chloro-9-[2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-9H-purine serves as a key nucleoside building block for the synthesis of antiviral agents and purine-based pharmaceutical intermediates. The protected ribose moiety enhances stability and facilitates selective functionalization at the C-6 position. Its well-documented reactivity enables reliable glycosylation and coupling protocols in medicinal chemistry workflows, supporting scalable synthesis of nucleoside analogs with proven biological activity.

General Information

CAS No. 39824-26-5
Cat. No. CS-W000282
Purity ≥97%
MDL No. MFCD03788833
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₅ClN₄O₄
Molecular Weight 326.74
Synonym(s) 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside)
SMILES CC1(C)O[C@H]2[C@@H](O1)[C@H](N3C(N=CN=C4Cl)=C4N=C3)O[C@@H]2CO

Computational Chemistry Data

TPSA 91.52
LogP 0.8895
H_Acceptors 8
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine

CAS No. 39824-26-5

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