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CS-W001157 4
Total: USD 88.00

(4-Benzamidophenyl)boronic acid

  • CAS No. 397843-80-0

  • Cat. No. CS-W012799
  • Purity≥96%
  • MDL No.MFCD08235089

*For research and further manufacturing use only, not for direct human use.

(4-Benzamidophenyl)boronic acid|CS-W012799

Structure of 397843-80-0

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General Information

  • CAS No. 397843-80-0
  • Cat. No. CS-W012799
  • Purity ≥96%
  • MDL No. MFCD08235089
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₂BNO₃
  • Molecular Weight 241.05
  • Synonym(s) 4-Benzamidophenylboronic acid
  • SMILES O=C(NC1=CC=C(B(O)O)C=C1)C2=CC=CC=C2

Description

(4-Benzamidophenyl)boronic acid features a boronic acid group appended to a para-substituted phenyl ring, where the amide functionality enhances solubility and electronic modulation. This scaffold integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, enabling efficient construction of biaryl architectures in medicinal chemistry and materials synthesis. The molecule exhibits bench-stable handling characteristics and tolerates diverse reaction environments.

Application

(4-Benzamidophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it well-suited for late-stage diversification in medicinal chemistry and materials synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   69.56
  • LogP   0.6187
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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