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Structure of 397-75-1
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2-Fluoro-4,5-dimethoxyaniline features a fluorine atom at the ortho position and two methoxy groups flanking the amino functionality, delivering enhanced electron density and improved solubility in polar organic solvents. This combination enables efficient coupling reactions in pharmaceutical intermediates and advanced materials synthesis under standard conditions.
2-Fluoro-4,5-dimethoxyaniline serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated heterocycles and bioactive scaffolds. Its ortho-fluoro and two methoxy groups provide enhanced metabolic stability and modulated electronic properties, facilitating coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: