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Structure of 396731-40-1
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tert-Butyl 3,5-dioxopiperidine-1-carboxylate features a rigid piperidine core with two ketone functionalities at the 3 and 5 positions, enabling efficient cyclization and functionalization. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring cyclic amine intermediates.
tert-Butyl 3,5-dioxopiperidine-1-carboxylate serves as a versatile scaffold for the synthesis of piperidine-based heterocycles, enabling efficient access to medicinally relevant frameworks. Its diketone functionality facilitates selective functionalization at C3 and C5, while the tert-butoxycarbonyl group provides stability and ease of removal under mild acidic conditions. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it a practical choice for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: