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CS-W001157 4
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2,2-Diphenylethan-1-amine

  • CAS No. 3963-62-0

  • Cat. No. CS-W010561
  • Purity≥97%
  • MDL No.MFCD00008143

*For research and further manufacturing use only, not for direct human use.

2,2-Diphenylethan-1-amine|CS-W010561

Structure of 3963-62-0

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General Information

  • CAS No. 3963-62-0
  • Cat. No. CS-W010561
  • Purity ≥97%
  • MDL No. MFCD00008143
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅N
  • Molecular Weight 197.28
  • Synonym(s) 2,2-Diphenylethylamine
  • SMILES NCC(C1=CC=CC=C1)C1=CC=CC=C1

Description

2,2-Diphenylethan-1-amine features a sterically hindered primary amine flanked by two aryl groups, conferring enhanced stability and resistance to oxidation. This configuration enables direct incorporation into conjugate addition reactions and facilitates the synthesis of functionalized aromatic scaffolds under mild conditions.

Application

2,2-Diphenylethan-1-amine serves as a versatile building block in synthetic organic chemistry, enabling the construction of biaryl-containing scaffolds and functionalized heterocycles. Its benzylic amine functionality exhibits good bench stability and compatibility with standard coupling reactions, facilitating efficient incorporation into complex molecular architectures. The molecule functions effectively as a precursor in the synthesis of pharmaceutically relevant frameworks and provides robust reactivity in nucleophilic transformations.

Synthesis

  • Route1

    References

    • Cha, Jin Soon; Brown, Herbert C. Journal of Organic Chemistry, 1993 , vol. 58, # 15 p. 3974 - 3979
  • Route2
    • (2-Nitroethane-1,1-diyl)dibenzene|CS-0287389
      5582-87-6
    • ~%
    • In-stock
      2,2-Diphenylethan-1-amine|CS-W010561
      3963-62-0

    References

    • Wanag; Platpiere; Mazkanowa Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 1535,1538 Chem.Abstr., 1950 , p. 1087
  • Route3
    • In-stock
      2,2-Dimethoxyethanamine|CS-0015304
      22483-09-6
    • null|null
      71-43-2
    • ~97%
    • In-stock
      2,2-Diphenylethan-1-amine|CS-W010561
      3963-62-0

    References

    • Klumpp, Douglas A; Sanchez Jr., Gregorio V; Aguirre, Sharon L; Zhang, Yun; de Leon, Sarah The Journal of organic chemistry, 2002 , vol. 67, # 14 p. 5028 - 5031

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.7772
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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