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CS-W001157 4
Total: USD 88.00

5-Bromonicotinoyl chloride

  • CAS No. 39620-02-5

  • Cat. No. CS-0695440
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromonicotinoyl chloride|CS-0695440

Structure of 39620-02-5

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General Information

  • CAS No. 39620-02-5
  • Cat. No. CS-0695440
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClNO
  • Molecular Weight 220.45
  • Synonym(s) None
  • SMILES ClC(=O)C1=CC(Br)=CN=C1

Description

5-Bromonicotinoyl chloride is a reactive acylating agent featuring a brominated pyridine ring, enabling efficient incorporation into complex molecular architectures. The compound exhibits high electrophilicity at the carbonyl center, facilitating rapid amide bond formation under mild conditions. This reactivity, combined with its stability during storage and ease of handling, makes it ideal for synthesizing bioactive heterocycles and functionalized intermediates in medicinal chemistry workflows.

Application

5-Bromonicotinoyl chloride serves as a versatile acylating agent for the synthesis of brominated nicotinamide derivatives and heterocyclic scaffolds. Its reactivity enables efficient amide bond formation under mild conditions, with good functional group tolerance and bench stability. The bromine substituent provides a handle for subsequent cross-coupling reactions, facilitating access to complex pharmaceutical intermediates and agrochemical building blocks.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2923
Class : 8 (6.1)
Packing Group : Ⅲ
Hazard Statements : H301-H311-H314-H331
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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