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Structure of 39615-34-4
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Cyclopropyl 2-methylphenyl ketone features a sterically constrained cyclopropyl group fused to a benzoyl scaffold with a para-methyl substituent. This arrangement imparts enhanced stability and modulates electronic properties, enabling selective reactivity in synthetic transformations. The compound serves as a key intermediate in medicinal chemistry applications, particularly in the development of bioactive scaffolds requiring precise steric and electronic tuning.
Cyclopropyl 2-methylphenyl ketone serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant scaffolds through standard carbonyl transformations. Its ortho-methyl substituent enhances metabolic stability and influences conformational rigidity, while the cyclopropyl group imparts distinct steric and electronic properties. The ketone functionality facilitates nucleophilic additions, reductions, and Grignard reactions, supporting diverse downstream derivatization. Bench-stable and readily purified by chromatography, it functions effectively in multi-step syntheses for target-oriented compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: