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Structure of 394-01-4
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4-Fluoro-2-nitrobenzoic acid features a fluorine atom at the para position and a nitro group at the ortho position relative to the carboxylic acid, creating a highly electron-deficient aromatic system. This combination enhances reactivity in nucleophilic substitution and facilitates coupling reactions under mild conditions. The molecule exhibits excellent bench stability and solubility in common organic solvents, enabling straightforward handling in synthetic workflows.
4-Fluoro-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to substituted heterocycles and bioactive scaffolds. Its ortho-nitro and meta-fluoro groups provide orthogonal reactivity for sequential functionalization, while the carboxylic acid facilitates direct coupling or derivatization. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: