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CS-W001157 4
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3-O-Methylgallic acid

  • CAS No. 3934-84-7

  • Cat. No. CS-0018329
  • Purity≥97%
  • MDL No.MFCD00016518

*For research and further manufacturing use only, not for direct human use.

3-O-Methylgallic acid|CS-0018329

Structure of 3934-84-7

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General Information

  • CAS No. 3934-84-7
  • Cat. No. CS-0018329
  • Purity ≥97%
  • MDL No. MFCD00016518
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₅
  • Molecular Weight None
  • Synonym(s) 3,4-Dihydroxy-5-methoxybenzoic acid
  • SMILES O=C(O)C1=CC(OC)=C(O)C(O)=C1

Description

3-O-Methylgallic acid features a methylated hydroxyl group at the C3 position of gallic acid, enhancing its metabolic stability and lipophilicity. This structural modification improves membrane permeability while retaining strong antioxidant activity. The compound serves as a key intermediate in synthesizing polyphenolic derivatives for pharmaceutical and nutraceutical applications.

Synthesis

  • Route1

    References

    • Saito, Shizuka; Kawabata, Jun Helvetica Chimica Acta, 2006 , vol. 89, # 7 p. 1395 - 1407
  • Route2
    • null|null
      246047-94-9
    • ~54%
    • In-stock
      3-O-Methylgallic acid|CS-0018329
      3934-84-7

    References

    • Feldman, Ken S.; Sambandam, Aruna; Bowers, Katherine E.; Appel, Heidi M. Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 5794 - 5803
  • Route3
    • Methyl 7-methoxy-2,2-diphenylbenzo[d][1,3]dioxole-5-carboxylate|CS-0562181
      102706-14-9
    • ~%
    • In-stock
      3-O-Methylgallic acid|CS-0018329
      3934-84-7

    References

    • Hodgson, Jonathan M.; Morton, Lincoln W.; Puddey, Ian B.; Beilin, Lawrence J.; Croft, Kevin D. Journal of Agricultural and Food Chemistry, 2000 , vol. 48, # 6 p. 2276 - 2280

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   86.99
  • LogP   0.8046
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   2

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