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CS-W001157 4
Total: USD 88.00

4-Nitro-3-(trifluoromethyl)aniline

  • CAS No. 393-11-3

  • Cat. No. CS-W015342
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Nitro-3-(trifluoromethyl)aniline|CS-W015342

Structure of 393-11-3

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General Information

  • CAS No. 393-11-3
  • Cat. No. CS-W015342
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅F₃N₂O₂
  • Molecular Weight 206.12
  • Synonym(s) None
  • SMILES FC(F)(F)C1=C([N+]([O-])=O)C=CC(N)=C1

Description

for synthesis

Application

4-Nitro-3-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized aromatic scaffolds. Its electron-deficient aryl core facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions. The nitro group offers direct reduction to an amine for further derivatization, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.16
  • LogP   2.1958
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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