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CS-W001157 4
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exo-Bicyclo[2.2.1]heptan-2-amine hydrochloride

  • CAS No. 39245-79-9

  • Cat. No. CS-0044000
  • Molecule weight147.65
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

exo-Bicyclo[2.2.1]heptan-2-amine hydrochloride|CS-0044000

Structure of 39245-79-9

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General Information

  • CAS No. 39245-79-9
  • Cat. No. CS-0044000
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClN
  • Molecular Weight 147.65
  • Synonym(s) Nsc141606
  • SMILES N[C@@H]1[C@H](C2)CC[C@H]2C1.[H]Cl

Description

exo-Bicyclo[2.2.1]heptan-2-amine hydrochloride delivers a rigid, sterically constrained amine scaffold ideal for medicinal chemistry applications. This bench-stable salt features a defined exo-orientation that enhances target selectivity in CNS-directed compound libraries. The protonated nitrogen facilitates salt formation and improves solubility in aqueous media without compromising stability.

Application

exo-Bicyclo[2.2.1]heptan-2-amine hydrochloride serves as a rigid, conformationally locked amine building block for medicinal chemistry and catalysis. Its stable bicyclic framework imparts excellent bench stability and predictable stereochemistry, enabling efficient incorporation into target molecules via standard functionalization protocols. The hydrochloride salt enhances solubility and purification ease in aqueous/organic workflows, making it ideal for high-throughput synthesis and structure-activity studies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5555
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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