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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-3-chloropropanoic acid

  • CAS No. 39217-38-4

  • Cat. No. CS-0100201
  • Purity≥95%
  • MDL No.MFCD01632068

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-chloropropanoic acid|CS-0100201

Structure of 39217-38-4

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General Information

  • CAS No. 39217-38-4
  • Cat. No. CS-0100201
  • Purity ≥95%
  • MDL No. MFCD01632068
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClNO₂
  • Molecular Weight 123.54
  • Synonym(s) 3-chloro-D-alanine
  • SMILES N[C@H](CCl)C(O)=O

Description

(S)-2-Amino-3-chloropropanoic acid is a chiral alpha-amino acid featuring a chlorine substituent at the beta position. This configuration imparts distinct stereochemical properties valuable in peptide synthesis and medicinal chemistry. The molecule exhibits enhanced metabolic stability compared to its unsubstituted analogs, enabling use in bioactive peptide scaffolds and enzyme inhibitor design under standard bench conditions.

Application

(S)-2-Amino-3-chloropropanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering a well-defined stereochemistry at the alpha carbon. Its amino and carboxylic acid functionalities enable straightforward coupling reactions, while the beta-chloro substituent provides a handle for subsequent nucleophilic substitution or elimination processes. The compound exhibits good bench stability and is compatible with standard purification protocols, facilitating its use in multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   -0.3629
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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