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CS-W001157 4
Total: USD 88.00

4-Amino-2,3-dichlorophenol

  • CAS No. 39183-17-0

  • Cat. No. CS-W006732
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,3-dichlorophenol|CS-W006732

Structure of 39183-17-0

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General Information

  • CAS No. 39183-17-0
  • Cat. No. CS-W006732
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Cl₂NO
  • Molecular Weight 178.02
  • Synonym(s) 2,3-Dichloro-4-aminophenol
  • SMILES OC1=CC=C(N)C(Cl)=C1Cl

Description

4-Amino-2,3-dichlorophenol features a chlorine-substituted phenolic scaffold with an electron-rich amino group at the para position, enabling robust coupling reactions. This bench-stable derivative integrates readily into synthetic sequences requiring halogen-directed functionalization or bioactive core construction under standard conditions.

Application

4-Amino-2,3-dichlorophenol serves as a versatile building block in medicinal chemistry, enabling the synthesis of chlorinated aromatic scaffolds via standard coupling reactions. Its amino and phenolic functionalities offer orthogonal reactivity for selective derivatization, while the dichloro substitution pattern enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in API intermediate development and high-throughput screening campaigns.

Synthesis

  • Route1
    • null|null
      111-48-8
    • null|null
      576-24-9
    • ~83%
    • In-stock
      4-Amino-2,3-dichlorophenol|CS-W006732
      39183-17-0

    References

    • Bayer Aktiengesellschaft Patent: US6124504 A1, 2000 ;
  • Route2
    • null|null
      576-24-9
    • ~%
    • In-stock
      4-Amino-2,3-dichlorophenol|CS-W006732
      39183-17-0

    References

    • Bayer Aktiengesellschaft Patent: US6124504 A1, 2000 ;
  • Route3
    • null|null
      3209-22-1
    • ~%
    • In-stock
      4-Amino-2,3-dichlorophenol|CS-W006732
      39183-17-0

    References

    • Bayer Aktiengesellschaft Patent: US5545754 A1, 1996 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   2.2812
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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