Lot numbers can be found on the outside label of a product:
L-Valyl-L-phenylalanine
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CAS No. 3918-92-1
- Cat. No. CS-7910
- Purity≥98%
- MDL No.MFCD00020423
*For research and further manufacturing use only, not for direct human use.
Structure of 3918-92-1
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General Information
- CAS No. 3918-92-1
- Cat. No. CS-7910
- Purity ≥98%
- MDL No. MFCD00020423
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₂₀N₂O₃
- Molecular Weight 264.32
- Synonym(s) Valylphenylalanine; H-VAL-PHE-OH
- SMILES O=C([C@@H](N)C(C)C)N[C@H](C(O)=O)CC1=CC=CC=C1
Description
L-Valyl-L-phenylalanine is a dipeptide featuring a valine residue linked via a peptide bond to phenylalanine, offering enhanced stability and solubility in aqueous systems. This combination enables efficient integration into synthetic peptide workflows, particularly in the development of bioactive sequences requiring hydrophobic character and metabolic resistance.
Application
L-Valyl-L-phenylalanine serves as a stable dipeptide building block for peptide synthesis, offering reliable coupling efficiency and orthogonal protection compatibility. Its well-defined stereochemistry ensures fidelity in sequence assembly, while the aliphatic valine side chain provides favorable solubility and reduced aggregation during solid-phase synthesis. This dipeptide functions effectively in the construction of bioactive peptides and pharmaceutical intermediates.
Synthesis
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Route1
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85310-50-5 - ~%
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In-stock
3918-92-1
References
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Zou, Weibiao; Ibrahem, Ismail; Dziedzic, Pawel; Sunden, Henrik; Cordova, Armando Chemical Communications, 2005 , # 39 p. 4946 - 4948 Title/Abstract Full Text View citing articles Show Details Dziedzic, Pawel; Zou, Weibiao; Hafren, Jonas; Cordova, Armando Organic and Biomolecular Chemistry, 2006 , vol. 4, # 1 p. 38 - 40
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Route2
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41445-88-9
- ~%
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In-stock
3918-92-1
References
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Cordova, Armando; Zou, Weibiao; Dziedzic, Pawel; Ibrahem, Ismail; Reyes, Efraim; Xu, Yongmei Chemistry - A European Journal, 2006 , vol. 12, # 20 p. 5383 - 5397
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Route3
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In-stock
1149-26-4 - ~%
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In-stock
3918-92-1
References
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Cordova, Armando; Zou, Weibiao; Dziedzic, Pawel; Ibrahem, Ismail; Reyes, Efraim; Xu, Yongmei Chemistry - A European Journal, 2006 , vol. 12, # 20 p. 5383 - 5397
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 92.42
- LogP 0.7818
- H_Acceptors 3
- H_Donors 3
- Rotatable_Bonds 6
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Key Words
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