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CS-W001157 4
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2-Chlorophenylboronic acid

  • CAS No. 3900-89-8

  • Cat. No. CS-D1476
  • Purity≥97%
  • MDL No.MFCD00674012

*For research and further manufacturing use only, not for direct human use.

2-Chlorophenylboronic acid|CS-D1476

Structure of 3900-89-8

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General Information

  • CAS No. 3900-89-8
  • Cat. No. CS-D1476
  • Purity ≥97%
  • MDL No. MFCD00674012
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BClO₂
  • Molecular Weight 156.37
  • Synonym(s) B-(2-Chlorophenyl)boronic acid; (o-Chlorophenyl)boronic acid; 2-Chlorobenzeneboronic acid; 2-Chlorophenylboronic Aicd; 2-Chlorophenylboronic acid
  • SMILES ClC1=CC=CC=C1B(O)O

Description

2-Chlorophenylboronic acid features a boronic acid group ortho to a chlorine substituent, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. This configuration enhances reactivity and stability under standard conditions, facilitating efficient C–C bond formation in complex molecule synthesis.

Synthesis

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    References

    • PHILADELPHIA HEALTH and EDUCATION CORPORATION; INSTITUTE FOR HEPATITIS AND VIRUS RESEARCH; KATSIKIS, Peter, D.; KINNEY, William, A.; ALMOND, Harold, R.; KHAN, Noshena Patent: WO2013/90725 A1, 2013 ; Location in patent: Page/Page column 68 ;
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    References

    • Yuen, Alexander K.L.; Hutton, Craig A. Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7899 - 7903
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      36692-27-0
    • In-stock
      Tributyl borate|CS-W014186
      688-74-4
    • ~%
    • In-stock
      2-Chlorophenylboronic acid|CS-D1476
      3900-89-8

    References

    • Branch; Yabroff; Bettman Journal of the American Chemical Society, 1934 , vol. 56, p. 937,938, 941

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.0198
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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