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CS-W001157 4
Total: USD 88.00

(4-(Pyrrolidine-1-carbonyl)phenyl)boronic acid

  • CAS No. 389621-81-2

  • Cat. No. CS-0175316
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-(Pyrrolidine-1-carbonyl)phenyl)boronic acid|CS-0175316

Structure of 389621-81-2

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General Information

  • CAS No. 389621-81-2
  • Cat. No. CS-0175316
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄BNO₃
  • Molecular Weight 219.04
  • Synonym(s) 4-[(1-Pyrrolidinyl)carbonyl]benzeneboronic Acid (contains varying amounts of Anhydride)
  • SMILES O=C(C1=CC=C(B(O)O)C=C1)N2CCCC2

Description

This boronate moiety integrates a pyrrolidine carbonyl group, enhancing solubility and stability while enabling efficient Suzuki-Miyaura coupling. The para-substituted arylboronic acid features a sterically accessible boron center, facilitating robust cross-coupling under standard conditions.

Application

(4-(Pyrrolidine-1-carbonyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The pyrrolidinyl carbonyl group enhances solubility and stability while maintaining compatibility with standard reaction conditions. Its robust boronic acid functionality facilitates reliable coupling with diverse aryl halides, supporting applications in medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   60.77
  • LogP   -0.3976
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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