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CS-W001157 4
Total: USD 88.00

5-Fluoroquinolin-8-ol

  • CAS No. 387-97-3

  • Cat. No. CS-W010847
  • Purity≥98%
  • MDL No.MFCD00059754

*For research and further manufacturing use only, not for direct human use.

5-Fluoroquinolin-8-ol|CS-W010847

Structure of 387-97-3

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General Information

  • CAS No. 387-97-3
  • Cat. No. CS-W010847
  • Purity ≥98%
  • MDL No. MFCD00059754
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆FNO
  • Molecular Weight 163.15
  • Synonym(s) 5-Fluorooxine
  • SMILES OC1=C2N=CC=CC2=C(F)C=C1

Description

5-Fluoroquinolin-8-ol features a fluorinated quinoline core with a phenolic hydroxyl group, offering enhanced electron-withdrawing character and improved solubility in polar solvents. This structural combination facilitates direct coupling reactions and enables integration into bioactive scaffolds for medicinal chemistry applications.

Synthesis

  • Route1

    References

    • Shi, Yue-Wen; Shi, Min-Min; Huang, Jia-Chi; Chen, Hong-Zheng; Wang, Mang; Liu, Xiao-Dong; Ma, Yu-Guang; Xu, Hai; Yang, Bing Chemical Communications, 2006 , # 18 p. 1941 - 1943
  • Route2

    References

    • Helin; Vanderwerf Journal of Organic Chemistry, 1952 , vol. 17, p. 229,230
  • Route3

    References

    • Helin; Vanderwerf Journal of Organic Chemistry, 1952 , vol. 17, p. 229,230

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.0795
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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